RESOURCES
Our Resources
From our live and on-demand webinars and white papers to the latest ebooks and scientific posters, Sinclair Research’s scientific
experts are here to help you overcome the obstacles in your drug development journey. Our online resources are designed to help
provide you with the scientific expertise you need to help you determine the next steps in your preclinical research development pipeline.
CHOOSING THE RIGHT MODEL: MINIATURE SWINE MODEL SELECTION CRITERIA FOR TOXICOLOGY AND PHARMACOLOGY STUDIES
Stream this webinar on demand presented at ACT 2021.
Beyond the FOB: Considerations for Development of Drugs with Neurologic Side Effects
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Preclinical Development: Early Considerations For Different Molecule Types
Stream this webinar presented by Tina Rogers, PhD, DABT, MBA
How to improve nonclinical study outcomes by mitigating research animal stress
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505(b)(2) Formulation Considerations for New Topical Drug Products
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Avoiding Obstacles When Outsourcing Your Nonclinical Research
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What Will Your CRO Partner Want To Know About Your Dermal Research Program?
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Comparison of Human, Porcine & Rodent Wound Healing with New Miniature Swine Study Data
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The Miniature Swine as a Model in Experimental and Translational Medicine
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Drug Dosages and Continuous Rate Infusion Protocols for Cardiovascular Research in Swine
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The Importance of Minipigs in Dermal Safety Assessment: An Overview
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Nonsurgical Vascular Catheterization Techniques in Swine
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Normal Organ Weight Data for the Yucatan Miniature Swine
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Normal Physiological and Pathological Values for the Sinclair Miniature Swine
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Handling, Husbandry and Injection Techniques in Swine
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Pigs in Toxicology: Breed Differences in Metabolism and Background Findings
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Chronic Intravascular Intervention in Swine: Peripheral Vessels
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Normal Data on Selected Lineages of Miniature Swine
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Short-acting and Long-acting Buprenorphine Therapeutic Drug Levels Following Single Subcutaneous Administration in Diabetic Yucatan Miniswine
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Laser Induced Choroidal Neovascularization (CNV) as a Model of Age-related Macular Degeneration (AMD) in the Minipig
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Porcine Integumentary System Models: Dermal Toxicology
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Minipig Model of Atopic Dermatitis: Assessment of In Vivo and In Vitro Activity of Recombinant Porcine Interleukin-4 and Interleukin-13
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Development of a Model of Dermal Inflammation and Irritation (Urticaria) in the Miniature Swine
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Acute Dermal Irritation Response in White Sinclair and Hanford Minipigs
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Identification of Immunophenotyping Biomarkers and Characterization of Peripheral Blood Lymphocytes Populations Distribution in Minipigs
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Assessment of Sexual Maturity in Three Lineages of Miniature Swine
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Miniature Swine as Endo-urological and Urological Models
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Experimental Induction of Allergic Contact Dermatitis in Sinclair, Hanford, and Yucatan Minipigs
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Tolerable Levels of Nonclinical Vehicles & Formulations Used in Studies by Multiple Routes in Multiple Species With Notes on Methods to Improve Utility
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Characterization of Transdermal Pharmacokinetics of Ketoprofen in Sinclair and Gottingen Minipigs
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Surgically Produced Volume and Pressure Overload Heart Failure Models in Swine
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Comparative Photomicrographic Examination of Integument From Eight Species of Mammals Including Two Lineages of Research Miniswine
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Chronic Intravascular Intervention in Swine: General Principles
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Validation of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments
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Pharmacokinetics of intravenous and oral metformin and r,s-verapamil in Sinclair, Hanford, Yucatan and Göttingen minipigs
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Surgical and Non-Surgical Drug Delivery Methods in Miniswine Models
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Sinclair – A Center of Excellence for Dermal Research
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Miniature Swine Breeds in Toxicology and Drug Safety Assessments: What to Expect during Clinical and Pathology Evaluations
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Cardiac Ischemia and Reperfusion as a Model of Myocardial Infarction in New Zealand White Rabbits
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Comparative Cardiovascular Physiology & Pathology in Selected Lineages of Minipigs: Relation to Drug Safety Evaluation
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Yucatan Miniature Swine Surgical Glaucoma Model Development and Response to Therapy
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Geometric Determinants of Full Thickness Wound Healing in Adult Male Yucatan Miniature Swine
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Tape Stripping Repetitions Reduce the Stratum Corneum Inversely in Yucatan Miniature Swine
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Differential Cardiovascular Physiology and Pathology in Selected Lineages of Miniature Swine and Comparison to Human
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Electrophysiological Assessment of Cardiac Complications in Chronic Diabetic Minipigs
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Characterization of Glomerular Filtration Rate and Renal Blood Flow of Diabetic Miniature Swine
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Handling Ease and Behavior Enhancement in Sinclair Miniature Swine
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Comparison of the Rabbit, Diabetic Miniature Swine and Non-Human Primate to Evaluate the Clinical Biopotency of Insulin Products
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Atherosclerosis and Related Nutritional Issues in Miniature Swine
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Oral Cyclosporine A Immunosuppressive Therapy Leads to Systemic Toxicity in the Royal College of Surgeons Rats
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Quantitation of Biomarkers Using Flow Cytometry in Clinical Pathology: Comparative Sensitivity and Reliability of Multi-Analytes Platform and Multiplex Cytometry in the Quantitation of Circulating Cytokines
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Comparative Sensitivity and Reliability of a Multi-Analytes Platform and a Multiplex Flow Cytometry in the Quantitation of Circulating Cytokines Level in a Mouse Model of Endotoxemia
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Miniature swine model of phototoxicity testing
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Development of a Functional ObservationalBattery in the Minipig for RegulatoryNeurotoxicity Assessments
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Preventing Process Drift While Improving Animal Welfare: Impact of Procedures Improvement in a Cat Colony
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Prevalence and Incidence of Cataracts in a Population of Diabetic Yucatan Miniswine
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Dermal Toxicology Application Area Changes as Compared to Theoretical Total Surface Area of Hanford Miniature Swine Over 18 Weeks
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Electroretinography (ERG) of C57BL/6 and NIH III Mice
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Histopathological Background Findings in Hanford Miniature Swine
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Effects of Minoxidil on Hair Growth in Minipigs
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Normal Physiological Values for Hanford Miniature Swine
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Characterization of Normal Skin Thickness for Various Body Regions, Ages and Genders of Yucatan Miniature Swine
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Pharmacodynamic Glycemia Effects from Rapid and Long-Acting Insulins Administered at Mealtime to Alloxan-Induced Diabetic Miniature Yucatan Swine
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Renal Complications in Chronic Diabetic Minipigs
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Basal and Short-term Food Denial Stress-Induced Plasma Cortisol in Four Lineages of Miniswine
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Blood Glucose (bG) Profiles Following IVGTT in Two Miniature Swine Lineages
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Targeting to Overshadow Fears and Anxiety in Miniature Swine
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Cutaneous Phototoxicity in White Hanford Miniature Swine
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Genetic Selection of Phenotype for Body Weight in the Miniature Swine
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White Hairless Miniature Swine Model for Dermal Studies
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Diabetes Mellitus & the Cardiometabolic Syndrome in Swine
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Dilated Cardiomyopathy and Ischemic Heart Failure Models in Pigs
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Interesting Facts About Miniature Swine and Bone Research
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Small Intestinal Anastomosis and Intestinal Infusion Catheter Implantation in Swine
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Ventricular Septal Defect (VSD) in Yucatan Miniature Swine
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Preventing Complications in the perioperative period in porcine surgery
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