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From our live and on-demand webinars and white papers to the latest ebooks and scientific posters, Sinclair Research’s scientific
experts are here to help you overcome the obstacles in your drug development journey. Our online resources are designed to help
provide you with the scientific expertise you need to help you determine the next steps in your preclinical research development pipeline.

    CHOOSING THE RIGHT MODEL: MINIATURE SWINE MODEL SELECTION CRITERIA FOR TOXICOLOGY AND PHARMACOLOGY STUDIES
    CHOOSING THE RIGHT MODEL: MINIATURE SWINE MODEL SELECTION CRITERIA FOR TOXICOLOGY AND PHARMACOLOGY STUDIES

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    Beyond the FOB: Considerations for development of drugs with neurologic side effects
    Beyond the FOB: Considerations for Development of Drugs with Neurologic Side Effects

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    CMC considerations for your ind-enabling program
    CMC Considerations For Your IND-Enabling Program

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    Molecule Considerations Webinar Laptop
    Preclinical Development: Early Considerations For Different Molecule Types

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    Selecting the Right Species for My Small Molecule Program
    Selecting the Right Species for My Small Molecule Program

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    Getting from R&D to IND
    Getting from R&D to IND

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    How to improve nonclinical study outcomes by mitigating research animal stress
    How to improve nonclinical study outcomes by mitigating research animal stress

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    505(b)(2) Formulation Considerations for New Topical Drug Products Laptop
    505(b)(2) Formulation Considerations for New Topical Drug Products

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    Avoiding Obstacles When Outsourcing Your Nonclinical Research
    Avoiding Obstacles When Outsourcing Your Nonclinical Research

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    How to optimize your safety pharmacology studies
    How to optimize your safety pharmacology studies

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    Scratching The Surface Of Dermal Testing Ebook
    Scratching the Surface of Dermal Testing

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    How Do I Get Into Phase 1 Trials With My Compound?
    How Do I Get Into Phase 1 Trials With My Compound?

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    The Minipig As A Model For Juvenile Toxicity Studies
    The Minipig As A Model For Juvenile Toxicity Studies

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    Scratching The Surface Of Dermal Testing Webinar Laptop
    Scratching the Surface of Dermal Testing

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    Miniature Swine Book of Normals
    Miniature Swine Book of Normals

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    GLP Validation Safety Pharmacology Data Review
    GLP Validation Safety Pharmacology Data Review

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    An Introduction to Ototoxicity
    An Introduction to Ototoxicity

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    What Will Your CRO Partner Want To Know About Your Dermal Research Program?
    What Will Your CRO Partner Want To Know About Your Dermal Research Program?

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    Anesthesia and Analgesia in Swine
    Anesthesia and Analgesia in Swine

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    Blood Collection in Swine
    Blood Collection in Swine

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    Comparative Anatomy of the Pig
    Comparative Anatomy of the Pig

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    Comparison of Human, Porcine & Rodent Wound Healing with New Miniature Swine Study Data
    Comparison of Human, Porcine & Rodent Wound Healing with New Miniature Swine Study Data

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    Cerebrospinal Fluid Collection in Swine
    Cerebrospinal Fluid Collection in Swine

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    The Miniature Swine as a Model in Experimental and Translational Medicine
    The Miniature Swine as a Model in Experimental and Translational Medicine

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    Drug Dosages and Continuous Rate Infusion Protocols for Cardiovascular Research in Swine
    Drug Dosages and Continuous Rate Infusion Protocols for Cardiovascular Research in Swine

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    Pain Assessment in Swine
    Pain Assessment in Swine

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    Perioperative Care of Swine
    Perioperative Care of Swine

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    The Importance of Minipigs in Dermal Safety Assessment: An Overview
    The Importance of Minipigs in Dermal Safety Assessment: An Overview

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    Nonsurgical Vascular Catheterization Techniques in Swine
    Nonsurgical Vascular Catheterization Techniques in Swine

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    Pain Control and Pain Research in Swine
    Pain Control and Pain Research in Swine

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    Normal Organ Weight Data for the Yucatan Miniature Swine
    Normal Organ Weight Data for the Yucatan Miniature Swine

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    Principles of Thoracic Surgery
    Principles of Thoracic Surgery

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    Normal Physiological and Pathological Values for the Sinclair Miniature Swine
    Normal Physiological and Pathological Values for the Sinclair Miniature Swine

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    Handling, Husbandry and Injection Techniques in Swine
    Handling, Husbandry and Injection Techniques in Swine

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    Pigs in Toxicology: Breed Differences in Metabolism and Background Findings
    Pigs in Toxicology: Breed Differences in Metabolism and Background Findings

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    Bone Marrow Access in Swine
    Bone Marrow Access in Swine

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    Porcine Integumentary System Models: Wound Healing
    Porcine Integumentary System Models: Wound Healing

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    Hemorrhagic Shock Models in Swine
    Hemorrhagic Shock Models in Swine

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    Vascular Studies in Minipigs
    Vascular Studies in Minipigs

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    Minipig Translational Research Models
    Minipig Translational Research Models

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    Chronic Intravascular Intervention in Swine: Peripheral Vessels
    Chronic Intravascular Intervention in Swine: Peripheral Vessels

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    Medical Device Implantation in Swine
    Medical Device Implantation in Swine

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    Normal Data on Selected Lineages of Miniature Swine
    Normal Data on Selected Lineages of Miniature Swine

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    Interventional Cardiovascular Procedures
    Interventional Cardiovascular Procedures

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    Short-acting and Long-acting Buprenorphine Therapeutic Drug Levels Following Single Subcutaneous Administration in Diabetic Yucatan Miniswine
    Short-acting and Long-acting Buprenorphine Therapeutic Drug Levels Following Single Subcutaneous Administration in Diabetic Yucatan Miniswine

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    Laser Induced Choroidal Neovascularization (CNV) as a Model of Age-related Macular Degeneration (AMD) in the Minipig
    Laser Induced Choroidal Neovascularization (CNV) as a Model of Age-related Macular Degeneration (AMD) in the Minipig

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    Porcine Integumentary System Models: Dermal Toxicology
    Porcine Integumentary System Models: Dermal Toxicology

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    Minipig Model of Atopic Dermatitis: Assessment of In Vivo and In Vitro Activity of Recombinant Porcine Interleukin-4 and Interleukin-13
    Minipig Model of Atopic Dermatitis: Assessment of In Vivo and In Vitro Activity of Recombinant Porcine Interleukin-4 and Interleukin-13

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    Trauma Models in Swine
    Trauma Models in Swine

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    Minipig Models for Toxicology and Pharmacology
    Minipig Models for Toxicology and Pharmacology

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    Portal Vein Catheterization in Swine
    Portal Vein Catheterization in Swine

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    Swine as Models in Dental and Oral Surgical Research
    Swine as Models in Dental and Oral Surgical Research

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    Development of a Model of Dermal Inflammation and Irritation (Urticaria) in the Miniature Swine
    Development of a Model of Dermal Inflammation and Irritation (Urticaria) in the Miniature Swine

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    Acute Dermal Irritation Response in White Sinclair and Hanford Minipigs
    Acute Dermal Irritation Response in White Sinclair and Hanford Minipigs

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    Identification of Immunophenotyping Biomarkers and Characterization of Peripheral Blood Lymphocytes Populations Distribution in Minipigs
    Identification of Immunophenotyping Biomarkers and Characterization of Peripheral Blood Lymphocytes Populations Distribution in Minipigs

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    Why Use Miniature Swine in Dermal Research?
    Why Use Miniature Swine in Dermal Research?

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    Assessment of Sexual Maturity in Three Lineages of Miniature Swine
    Assessment of Sexual Maturity in Three Lineages of Miniature Swine

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    Miniature Swine as Endo-urological and Urological Models
    Miniature Swine as Endo-urological and Urological Models

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    Experimental Induction of Allergic Contact Dermatitis in Sinclair, Hanford, and Yucatan Minipigs
    Experimental Induction of Allergic Contact Dermatitis in Sinclair, Hanford, and Yucatan Minipigs

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    Tolerable Levels of Nonclinical Vehicles & Formulations Used in Studies by Multiple Routes in Multiple Species With Notes on Methods to Improve Utility
    Tolerable Levels of Nonclinical Vehicles & Formulations Used in Studies by Multiple Routes in Multiple Species With Notes on Methods to Improve Utility

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    Characterization of Transdermal Pharmacokinetics of Ketoprofen in Sinclair and Gottingen Minipigs
    Characterization of Transdermal Pharmacokinetics of Ketoprofen in Sinclair and Gottingen Minipigs

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    Surgically Produced Volume and Pressure Overload Heart Failure Models in Swine
    Surgically Produced Volume and Pressure Overload Heart Failure Models in Swine

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    Common Bile Duct Cannulation in Swine
    Common Bile Duct Cannulation in Swine

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    Comparative Photomicrographic Examination of Integument From Eight Species of Mammals Including Two Lineages of Research Miniswine
    Comparative Photomicrographic Examination of Integument From Eight Species of Mammals Including Two Lineages of Research Miniswine

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    Chronic Intravascular Intervention in Swine: General Principles
    Chronic Intravascular Intervention in Swine: General Principles

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    Validation of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments
    Validation of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments

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    Pharmacokinetics of intravenous and oral metformin and r,s-verapamil in Sinclair, Hanford, Yucatan and Göttingen minipigs
    Pharmacokinetics of intravenous and oral metformin and r,s-verapamil in Sinclair, Hanford, Yucatan and Göttingen minipigs

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    MHC Defined Lineages for Transplantation
    MHC Defined Lineages for Transplantation

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    Neurodegenerative Disease Models in Swine
    Neurodegenerative Disease Models in Swine

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    Surgical and Non-Surgical Drug Delivery Methods in Miniswine Models
    Surgical and Non-Surgical Drug Delivery Methods in Miniswine Models

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    Sinclair – A Center of Excellence for Dermal Research
    Sinclair – A Center of Excellence for Dermal Research

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    Miniature Swine Breeds in Toxicology and Drug Safety Assessments: What to Expect during Clinical and Pathology Evaluations
    Miniature Swine Breeds in Toxicology and Drug Safety Assessments: What to Expect during Clinical and Pathology Evaluations

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    Cardiac Ischemia and Reperfusion as a Model of Myocardial Infarction in New Zealand White Rabbits
    Cardiac Ischemia and Reperfusion as a Model of Myocardial Infarction in New Zealand White Rabbits

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    Comparative Cardiovascular Physiology & Pathology in Selected Lineages of Minipigs: Relation to Drug Safety Evaluation
    Comparative Cardiovascular Physiology & Pathology in Selected Lineages of Minipigs: Relation to Drug Safety Evaluation

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    Yucatan Miniature Swine Surgical Glaucoma Model Development and Response to Therapy
    Yucatan Miniature Swine Surgical Glaucoma Model Development and Response to Therapy

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    Geometric Determinants of Full Thickness Wound Healing in Adult Male Yucatan Miniature Swine
    Geometric Determinants of Full Thickness Wound Healing in Adult Male Yucatan Miniature Swine

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    Tape Stripping Repetitions Reduce the Stratum Corneum Inversely in Yucatan Miniature Swine
    Tape Stripping Repetitions Reduce the Stratum Corneum Inversely in Yucatan Miniature Swine

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    Orthopedic and Cartilage Models
    Orthopedic and Cartilage Models

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    Differential Cardiovascular Physiology and Pathology in Selected Lineages of Miniature Swine and Comparison to Human
    Differential Cardiovascular Physiology and Pathology in Selected Lineages of Miniature Swine and Comparison to Human

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    Electrophysiological Assessment of Cardiac Complications in Chronic Diabetic Minipigs
    Electrophysiological Assessment of Cardiac Complications in Chronic Diabetic Minipigs

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    Characterization of Glomerular Filtration Rate and Renal Blood Flow of Diabetic Miniature Swine
    Characterization of Glomerular Filtration Rate and Renal Blood Flow of Diabetic Miniature Swine

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    Catheterization of the Pancreatic Duct
    Catheterization of the Pancreatic Duct

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    Minipigs: Applications in Toxicology
    Minipigs: Applications in Toxicology

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    Handling Ease and Behavior Enhancement in Sinclair Miniature Swine
    Handling Ease and Behavior Enhancement in Sinclair Miniature Swine

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    Comparison of the Rabbit, Diabetic Miniature Swine and Non-Human Primate to Evaluate the Clinical Biopotency of Insulin Products
    Comparison of the Rabbit, Diabetic Miniature Swine and Non-Human Primate to Evaluate the Clinical Biopotency of Insulin Products

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    Atherosclerosis and Related Nutritional Issues in Miniature Swine
    Atherosclerosis and Related Nutritional Issues in Miniature Swine

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    Oral Cyclosporine A Immunosuppressive Therapy Leads to Systemic Toxicity in the Royal College of Surgeons Rats
    Oral Cyclosporine A Immunosuppressive Therapy Leads to Systemic Toxicity in the Royal College of Surgeons Rats

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    Quantitation of Biomarkers Using Flow Cytometry in Clinical Pathology: Comparative Sensitivity and Reliability of Multi-Analytes Platform and Multiplex Cytometry in the Quantitation of Circulating Cytokines
    Quantitation of Biomarkers Using Flow Cytometry in Clinical Pathology: Comparative Sensitivity and Reliability of Multi-Analytes Platform and Multiplex Cytometry in the Quantitation of Circulating Cytokines

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    Comparative Sensitivity and Reliability of a Multi-Analytes Platform and a Multiplex Flow Cytometry in the Quantitation of Circulating Cytokines Level in a Mouse Model of Endotoxemia
    Comparative Sensitivity and Reliability of a Multi-Analytes Platform and a Multiplex Flow Cytometry in the Quantitation of Circulating Cytokines Level in a Mouse Model of Endotoxemia

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    Miniature swine model of phototoxicity testing
    Miniature swine model of phototoxicity testing

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    Development of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments
    Development of a Functional ObservationalBattery in the Minipig for RegulatoryNeurotoxicity Assessments

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    Preventing Process Drift While Improving Animal Welfare: Impact of Procedures Improvement in a Cat Colony
    Preventing Process Drift While Improving Animal Welfare: Impact of Procedures Improvement in a Cat Colony

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    Prevalence and Incidence of Cataracts in a Population of Diabetic Yucatan Miniswine
    Prevalence and Incidence of Cataracts in a Population of Diabetic Yucatan Miniswine

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    Dermal Toxicology Application Area Changes as Compared to Theoretical Total Surface Area of Hanford Miniature Swine Over 18 Weeks
    Dermal Toxicology Application Area Changes as Compared to Theoretical Total Surface Area of Hanford Miniature Swine Over 18 Weeks

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    Electroretinography (ERG) of C57BL/6 and NIH III Mice
    Electroretinography (ERG) of C57BL/6 and NIH III Mice

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    Histopathological Background Findings in Hanford Miniature Swine
    Histopathological Background Findings in Hanford Miniature Swine

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    Effects of Minoxidil on Hair Growth in Minipigs
    Effects of Minoxidil on Hair Growth in Minipigs

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    Normal Physiological Values for Hanford Miniature Swine
    Normal Physiological Values for Hanford Miniature Swine

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    Characterization of Normal Skin Thickness for Various Body Regions, Ages and Genders of Yucatan Miniature Swine
    Characterization of Normal Skin Thickness for Various Body Regions, Ages and Genders of Yucatan Miniature Swine

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    Pharmacodynamic Glycemia Effects from Rapid and Long-Acting Insulins Administered at Mealtime to Alloxan-Induced Diabetic Miniature Yucatan Swine
    Pharmacodynamic Glycemia Effects from Rapid and Long-Acting Insulins Administered at Mealtime to Alloxan-Induced Diabetic Miniature Yucatan Swine

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    Miniature Swine Model of Phototoxicity Testing
    Miniature Swine Model of Phototoxicity Testing

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    Renal Complications in Chronic Diabetic Minipigs
    Renal Complications in Chronic Diabetic Minipigs

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    Basal and Short-term Food Denial Stress-Induced Plasma Cortisol in Four Lineages of Miniswine
    Basal and Short-term Food Denial Stress-Induced Plasma Cortisol in Four Lineages of Miniswine

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    Blood Glucose (bG) Profiles Following IVGTT in Two Miniature Swine Lineages
    Blood Glucose (bG) Profiles Following IVGTT in Two Miniature Swine Lineages

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    Targeting to Overshadow Fears and Anxiety in Miniature Swine
    Targeting to Overshadow Fears and Anxiety in Miniature Swine

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    Cutaneous Phototoxicity in White Hanford Miniature Swine
    Cutaneous Phototoxicity in White Hanford Miniature Swine

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    Genetic Selection of Phenotype for Body Weight in the Miniature Swine
    Genetic Selection of Phenotype for Body Weight in the Miniature Swine

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    White Hairless Miniature Swine Model for Dermal Studies
    White Hairless Miniature Swine Model for Dermal Studies

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    Developmental Guidelines in Swine
    Developmental Guidelines in Swine

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    Diabetes in Miniature Swine
    Diabetes in Miniature Swine

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    Diabetes Mellitus & the Cardiometabolic Syndrome in Swine
    Diabetes Mellitus & the Cardiometabolic Syndrome in Swine

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    Dilated Cardiomyopathy and Ischemic Heart Failure Models in Pigs
    Dilated Cardiomyopathy and Ischemic Heart Failure Models in Pigs

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    Interesting Facts About Miniature Swine and Bone Research
    Interesting Facts About Miniature Swine and Bone Research

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    Small Intestinal Anastomosis and Intestinal Infusion Catheter Implantation in Swine
    Small Intestinal Anastomosis and Intestinal Infusion Catheter Implantation in Swine

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    Regulatory Dermal Toxicology Testing
    Regulatory Dermal Toxicology Testing

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    Spontaneously Regressing Malignant Melanomas
    Spontaneously Regressing Malignant Melanomas

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    Ventricular Septal Defect (VSD) in Yucatan Miniature Swine
    Ventricular Septal Defect (VSD) in Yucatan Miniature Swine

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    Miniature Swine in Osteoporosis Research
    Miniature Swine in Osteoporosis Research

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    Cartilage & Bone Models in Swine
    Cartilage & Bone Models in Swine

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    Sinclair Miniature Swine Osteopenia Model
    Sinclair Miniature Swine Osteopenia Model

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    Behavior, Socialization & Enrichment of Minipigs
    Behavior, Socialization & Enrichment of Minipigs

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    Preventing Complications in the perioperative period in porcine surgery
    Preventing Complications in the perioperative period in porcine surgery

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