PREVENTING COMPLICATIONS IN THE PERIOPERATIVE PERIOD IN PORCINE SURGERY
Many of the models for which swine have been developed involve anesthesia and surgery. Complications due to the physiologic effects of anesthetic and analgesic protocols are a significant factor in mortality and other physiologic complications in porcine research models. Inappropriate surgical technique, even for minor surgeries, can also significantly complicate the production of any of the surgically produced models.
The author has >40 years of experience involving surgery and anesthesia in many diverse porcine models. This manuscript describes common perioperative complications which may be encountered performing research in swine. The complications described below are more frequently encountered when investigators and veterinary staff who have limited experience with the species. The general approach that is recommended is to prevent complications rather than treating them after they have developed.
M. Michael Swindle, DVM, Professor Emeritus, Medical University of SC; Veterinary Consultant